Member’s paper

Go to all Publications

Type of Paper publication
Title: Impaired renal function is associated with mortality in kidney-transplanted patients.
Authors: Remport A, Molnar MZ, Ambrus C, Keszei A, Torok S, Vamos EP, Kiss I, Jaray J, Novak M, Rosivall L, Mucsi I.
Conference:
Year: 2010
Journal: International Urology and Nephrology
Volume 42
Issue 3
Page(s) 799-809
Abstract* INTRODUCTION: To date, only a few, at times conflicting, reports suggested that renal function and mortality are associated in kidney-transplanted patients. In our prevalence cohort study, we tested the hypothesis that renal function is associated with mortality in transplanted patients. METHODS: Data from 985 transplanted patients were analyzed. Socio-demographic parameters, laboratory data, medical and transplant history, type of immunosuppression and estimated glomerular filtration rate were tabulated at baseline. Data on 5-year outcome were collected prospectively. RESULTS: In multivariate Cox proportional hazard models, the estimated glomerular filtration rate measured at baseline significantly predicted mortality [hazard ratio (HR)(for each 10 ml/min decrease) = 1.271; 95% confidence interval (CI): 1.121-1.440] after adjustment for several covariables. Additionally, in multivariate Cox proportional hazard models, chronic kidney disease stage 4-5 (HR = 2.678; 95% CI: 1.494-4.802) significantly increased the mortality hazard compared to chronic kidney disease stage 1-2. CONCLUSIONS: Renal function is significantly and independently associated with mortality over 5 years in kidney-transplanted patients among whom mycophenolate mofetil use was very prevalent.
Link View Paper Online
Publication File* See File
DCAP: No File Attached
Presentation No File Attached
Published?
Expected Publishing Date
Grant Number none
Reb Number* none
Accepted: yes
Do File: No File Attached