Member’s paper

Go to all Publications

Type of Paper publication
Title: Depressive symptoms and mortality in patients after kidney transplantation: a prospective prevalent cohort study.
Authors: Novak M, Molnar MZ, Szeifert L, Kovacs AZ, Vamos EP, Zoller R, Keszei A, Mucsi I.
Year: 2010
Journal: Psychosomatic Medicine
Volume 72
Issue 6
Page(s) 527-34
Abstract* OBJECTIVE: To analyze in a prospective cohort study if depressive symptoms are an independent predictor of mortality in kidney transplant recipients. METHODS: Data from 840 transplanted patients followed at a single outpatient transplant center were analyzed. Sociodemographic parameters and clinical data were collected at enrollment (between August 2002 and February 2003). Participants completed the Center for Epidemiologic Studies-Depression (CES-D) scale. Depression was defined as CES-D score of > or = 18. Data on 5-year outcomes (death censored graft loss or mortality) were collected. RESULTS: The prevalence of depression was 22%. Mortality was higher (21% versus 13%; p = .004) in patients with versus without depression. In a multivariate Cox proportional hazard model, both the baseline CES-D score (hazard ratio(for each 1-point increase) = 1.02; 95% confidence interval, 1.00-1.04) and the presence of depression at baseline (hazard ratio(presence) = 1.66; 95% confidence interval, 1.12-2.47) were significantly associated with mortality. The baseline CES-D score also significantly predicted death censored graft loss (hazard ratio(for each 1-point increase) = 1.03; 95% confidence interval, 1.01-1.05). CONCLUSION: Depressive symptoms are an independent predictor of mortality in kidney transplanted patients.
Link View Paper Online
Publication File* See File
DCAP: No File Attached
Presentation No File Attached
Expected Publishing Date
Grant Number none
Reb Number* none
Accepted: yes
Do File: No File Attached