Member’s paper

Go to all Publications

Type of Paper publication
Title: Association of pre-transplant dialysis duration with outcome in kidney transplant recipients: a prevalent cohort study.
Authors: Remport A, Keszei A, Vamos EP, Novak M, Jaray J, Rosivall L, Mucsi I, Molnar MZ.
Year: 2011
Journal: International Urology and Nephrology
Volume 43
Issue 1
Page(s) 215-24
Abstract* INTRODUCTION: Dialysis treatment prior to transplantation may contribute to premature mortality and graft loss in kidney-transplanted patients. In this prevalent cohort study (TransQol-HU Study), we analyzed the association between pre-transplant dialysis duration versus mortality and death-censored graft loss in kidney-transplanted patients. METHODS: Data from 926 kidney-transplanted patients followed at a single outpatient transplant center were analyzed. Socio-demographic parameters, laboratory data, medical history, donor characteristics and information on co-morbidities were collected at baseline. Data on 5-year outcome (graft loss, mortality) were collected. RESULTS: In multivariate analyses, pre-transplant dialysis duration was an independent risk factor for mortality (HR(for each month increase) = 1.011; 95% CI: 1.005-1.016) and also for death-censored graft loss (HR(for each month increase) = 1.008; 95% CI: 1.001-1.015) after adjustment for several co-variables. In the multivariate model, patients with less than 1 year (HR = 0.498; 95% CI: 0.302-0.820; P = 0.006) and 1-3 years (HR = 0.577; 95% CI: 0.371-0.899; P = 0.015) of pre-transplant dialysis had significantly better survival after transplantation compared to those with more than 3 years on dialysis. CONCLUSIONS: These findings add further strength to existing evidence about the significant association between longer pre-transplant dialysis duration and poor outcome in kidney-transplanted patients.
Link View Paper Online
Publication File* See File
DCAP: No File Attached
Presentation No File Attached
Expected Publishing Date
Grant Number none
Reb Number* none
Accepted: yes
Do File: No File Attached